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Ipamorelin – Research Peptide

A short synthetic secretagogue notable for how little it disturbs other pituitary hormones.

Price range: $20.00 through $40.00

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* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

What Ipamorelin is A five-residue peptide acting at the growth hormone secretagogue receptor, the same receptor targeted by ghrelin. It is studied largely because of its selectivity: in the published work it releases growth hormone without the cortisol and prolactin changes seen with earlier secretagogues. Mechanism Agonist at GHS-R1a on pituitary somatotrophs, acting through a pathway distinct from the GHRH receptor. The two can therefore be studied together, and the literature reports additive release when both are stimulated. Where it appears in research GHS-R1a receptor selectivity profiling Comparative secretagogue studies Ghrelin pathway research Combined GHRH and GHS-R stimulation models History Developed at Novo Nordisk in the 1990s during a programme searching for secretagogues more selective than the earlier GHRP series. Described by Raun and colleagues in 1998.

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