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TB-500 – Research Peptide Price range: $25.00 through $110.00
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Tesamorelin – Research Peptide

A full-length GHRH analogue carrying an N-terminal hexenoyl group, and one of the few GHRH compounds to complete regulatory review.

Price range: $30.00 through $180.00

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* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

What Tesamorelin is A 44-residue analogue of human growth-hormone-releasing hormone with a trans-3-hexenoyl group attached at the N-terminus. That modification resists enzymatic degradation while leaving receptor binding intact, giving a longer-lived analogue than the native hormone. Mechanism Binds the GHRH receptor on pituitary somatotrophs, raising cAMP and stimulating synthesis and release of endogenous growth hormone. Because it acts on the pituitary rather than replacing GH directly, downstream feedback regulation remains in the loop. Where it appears in research GHRH receptor pharmacology Visceral adipose tissue models IGF-1 axis studies N-terminal modification and peptide stability History Developed by Theratechnologies in Canada and approved by the FDA in 2010 under the name Egrifta for a specific lipodystrophy indication. It remains one of very few GHRH analogues to have completed full clinical development.

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