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Semax – Research Peptide

A heptapeptide built from a corticotropin fragment, stabilised by a tripeptide tail.

Price range: $20.00 through $40.00

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* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

What Semax is Semax couples the 4-10 fragment of adrenocorticotropic hormone, which carries the behavioural activity without the hormonal activity, to a C-terminal Pro-Gly-Pro that markedly slows enzymatic degradation. The result is a stable peptide with no corticotropic effect. Mechanism Reported to raise brain-derived neurotrophic factor and its receptor TrkB in hippocampal tissue, alongside effects on dopaminergic and serotonergic transmission. Also studied for influence on the plasminogen activator system. Where it appears in research BDNF and neurotrophin expression Neuroprotection models Cognitive and behavioural assays Peptide stabilisation strategies History Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences in the late 1980s and 1990s. Registered as a medicine in Russia, though it has not been through FDA or EMA review, so most literature is Russian-language.

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